Em/D# guitar chord
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About Em/D# — uncommon voicings
Em/D# is D#, E, G and B — with D♯ put in the bass.
It sounds like the minor triad it is, resting on a different floor. If D♯ is already one of the chord’s notes this is an inversion, and if it is not it is a new colour under an unchanged chord; either way the reason to reach for it is a bass line that walks by step where root-position chords would leap.
Inversion or pedal — the harmony is unchanged; only the bass moves.
Also written Em over D# or Em with D# in the bass.
What these less common shapes are
What to play over Em/D#
Every note of Em/D# is in E harmonic minor and E melodic minor.
Each of those is a page: the scale across the neck, and the chords it harmonises into — which is where Em/D# sits in it. Every scale.
Chords near Em/D#
Change one note of Em/D# and you have (drop the major seventh), (the minor third becomes the major third), (the major seventh becomes the sixth), (the major seventh becomes the flat seventh), (the fifth becomes the flat fifth) or (add the ninth).
Em/D# is a slash chord — a triad over a named bass note. Slash chords on every root.
The common shapes and the derived voicings come from different places, and both are explained in how this site is built.